How To Install esearch on CentOS 8

In this tutorial, we will discuss How To Install esearch on CentOS 8 using dnf and yum package managers. Also, we will demonstrate how to uninstall and update esearch as well.

One-liner Install Command

If you are only interested in the installation command, here is a quick answer for you:

sudo yum makecache && sudo yum -y install ncbi-entrez-direct
or if you use dnf:
sudo dnf makecache && sudo dnf -y install ncbi-entrez-direct

But if you are interested in the details with step-by-step instructions, the following information will be helpful.

What is esearch and How to Install It?

First things first, you will need access to a server or computer running CentOS 8. This guide was written specifically with a server running CentOS 8 in mind, although it should also work on older, supported versions of the operating system.

Also, make sure you are running a regular, non-root user with sudo privileges configured on your server. When you have an account available, log in as your non-root user to begin.

There are several ways to install esearch on CentOS 8. You can use (links are clickable):

In the following sections, we will describe each method in detail. You can choose one of them or refer to the recommended one.

Install esearch on CentOS 8 using dnf

First, update dnf packages database with dnf by running the next command:

sudo dnf makecache --refresh

After updating database, You can install esearch using dnf by running the following command:

sudo dnf -y install ncbi-entrez-direct

Install esearch on CentOS 8 using yum

Because esearch is available in CentOS 8’s default repositories, it is possible to install it from these repositories using the yum packaging system.

To begin, update local packages database with yum using the following command.

sudo yum makecache --refresh

Now can install esearch package on your server/computer by running the following command:

sudo yum -y install ncbi-entrez-direct

How to upgrade (update) a single package esearch using yum?

To update all the packages available on the system:

yum update

If you want to update a specific package like esearch in this example you should use the following command:

yum update ncbi-entrez-direct

To downgrade a package to an earlier version:

yum downgrade ncbi-entrez-direct

How to Upgrade esearch on CentOS 8 with dnf?

When you run the dnf update, all system packages with available updates are updated. However, if you want to upgrade a single package, then you would have to pass the package name as the argument to the dnf update command.

dnf update ncbi-entrez-direct

How To remove esearch from CentOS 8

To uninstall only the esearch package you can execute the following command:

sudo dnf remove ncbi-entrez-direct

Extra info and code examples

Entrez Direct (EDirect) is an advanced method for accessing NCBI's set of interconnected databases (publication, sequence, structure, gene, variation, expression, etc.) from a terminal window or script. Functions take search terms from command-line arguments. Individual operations are combined to build multi-step queries. Record retrieval and formatting normally complete the process. EDirect also provides an argument-driven function that simplifies the extraction of data from document summaries or other results that are returned in structured XML format. This can eliminate the need for writing custom software to answer ad hoc questions. Queries can move seamlessly between EDirect commands and UNIX utilities or scripts to perform actions that cannot be accomplished entirely within Entrez.


You now have a full guide on how to install esearch using dnf and yum package managers. Also, we showed how to update manually as a single package and different ways to uninstall the esearch from CentOS 8.

See also:

How To Install esearch on CentOS 8

How To Install esearch on Ubuntu 22.04

How To Install esearch on Ubuntu 21.04

How To Install esearch on Kali Linux

How To Install esearch on Debian 11

How To Install esearch on Fedora 34