How To Install disulfinder on CentOS 8

One-liner Install Command

If you are only interested in the installation command, here is a quick answer for you:

sudo yum makecache && sudo yum -y install disulfinder

sudo dnf makecache && sudo dnf -y install disulfinder

But if you are interested in the details with step-by-step instructions, the following information will be helpful.

What is disulfinder and How to Install It?

First things first, you will need access to a server or computer running CentOS 8. This guide was written specifically with a server running CentOS 8 in mind, although it should also work on older, supported versions of the operating system.

Also, make sure you are running a regular, non-root user with sudo privileges configured on your server. When you have an account available, log in as your non-root user to begin.

There are several ways to install disulfinder on CentOS 8. You can use (links are clickable):

In the following sections, we will describe each method in detail. You can choose one of them or refer to the recommended one.

Install disulfinder on CentOS 8 using dnf

First, update dnf packages database with dnf by running the next command:

sudo dnf makecache --refresh

After updating database, You can install disulfinder using dnf by running the following command:

sudo dnf -y install disulfinder

Install disulfinder on CentOS 8 using yum

Because disulfinder is available in CentOS 8’s default repositories, it is possible to install it from these repositories using the yum packaging system.

To begin, update local packages database with yum using the following command.

sudo yum makecache --refresh

Now can install disulfinder package on your server/computer by running the following command:

sudo yum -y install disulfinder

How to upgrade (update) a single package disulfinder using yum?

To update all the packages available on the system:

yum update

If you want to update a specific package like disulfinder in this example you should use the following command:

yum update disulfinder

To downgrade a package to an earlier version:

yum downgrade disulfinder

How to Upgrade disulfinder on CentOS 8 with dnf?

When you run the dnf update, all system packages with available updates are updated. However, if you want to upgrade a single package, then you would have to pass the package name as the argument to the dnf update command.

dnf update disulfinder

How To remove disulfinder from CentOS 8

To uninstall only the disulfinder package you can execute the following command:

sudo dnf remove disulfinder

Extra info and code examples

'disulfinder' is for predicting the disulfide bonding state of cysteines and their disulfide connectivity starting from sequence alone. Disulfide bridges play a major role in the stabilization of the folding process for several proteins. Prediction of disulfide bridges from sequence alone is therefore useful for the study of structural and functional properties of specific proteins. In addition, knowledge about the disulfide bonding state of cysteines may help the experimental structure determination process and may be useful in other genomic annotation tasks. 'disulfinder' predicts disulfide patterns in two computational stages: (1) the disulfide bonding state of each cysteine is predicted by a BRNN-SVM binary classifier; (2) cysteines that are known to participate in the formation of bridges are paired by a Recursive Neural Network to obtain a connectivity pattern.

Conclusion

You now have a full guide on how to install disulfinder using dnf and yum package managers. Also, we showed how to update manually as a single package and different ways to uninstall the disulfinder from CentOS 8.

See also: